Acifix Rabeprazole Capsule 20mg
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About this item
- It is a well-tolerated medicine and provides relief for a long time.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Acifix can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Product Specifications
See all 13Product Description
Medicine Overview
Introduction
Acifix is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and some other stomach conditions associated with excessive acid production.
Acifix is also used to prevent stomach ulcers and acidity that may be seen with the prolonged use of pain-killers. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying condition and how you respond to the medicine. Try to take it regularly at the same time each day as advised by your doctor. You should keep on taking it as prescribed even if your symptoms disappear quickly. You may be able to help improve your symptoms by eating smaller meals more often and avoiding caffeinated drinks like tea and coffee, and spicy or fatty foods.
The most common side effects that may be seen with this medicine include nausea, vomiting headache, dizziness, flatulence, diarrhea, and stomach pain. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. Long-term use (more than 1 year) may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Low blood magnesium levels (hypomagnesemia) have been seen in some people taking this medicine for 3 months or more. This may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this.
Acifix is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.
Uses of Acifix
- Gastroesophageal reflux disease (Acid reflux)
- Peptic ulcer disease
Side effects of Acifix
Common
- Diarrhea
- Dizziness
- Flatulence
- Headache
- Nausea
- Sore throat
- Stomach pain
- Vomiting
How to use Acifix
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acifix is to be taken empty stomach.
How Acifix works
Acifix is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
What if you forget to take Acifix?
If you miss a dose of Acifix, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Brief Description & Clinical Guide
Indication
Peptic ulcer disease, H. pylori infection, Gastro-oesophageal reflux disease, Paediatric GERD
Administration
Administer with or without meals
Adult Dose
Oral
Gastro-oesophageal reflux disease
Adult: 20 mg daily for 4-8 wk. Maintenance: 10 or 20 mg/day. All doses to be taken once in the morning.
Zollinger-Ellison syndrome
Adult: Initially, 60 mg once in the morning, adjusted to max dose of 120 mg/day if needed. Daily doses >100 mg should be given in 2 divided doses.
Peptic ulcer
Adult: 20 mg once in the morning for 4-8 wk (duodenal ulcer) or for 6-12 wk (gastric ulcer).
H.pylori infection
Adult: 1-wk triple therapy: 20 mg bid combined w/ clarithromycin 500 mg bid and amoxicillin 1 g bid or combined w/ clarithromycin 250 mg bid and metronidazole 400 mg bid.
Erosive oesophagitis
Adult: 20 mg/day for 4-8 wk. May continue for another 8 wk if healing is incomplete. Maintenance: 10 or 20 mg/day. All doses to be taken once in the morning.
Elderly: No dosage adjustment needed.
Hepatic impairment: No dosage adjustment needed.
Child Dose
Delayed-release capsule (sprinkles)
Technical Details & Specifications
13 specifications| Generic Name | Rabeprazole |
| Form | Capsule |
| Strength | 20mg |
| Base Unit | Capsule × 1 |
| Sales Unit | Strip × 10 |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Indication | Peptic ulcer disease, H. pylori infection, Gastro-oesophageal reflux disease, Paediatric GERD |
| Administration | Administer with or without meals |
| Adult Dose | OralGastro-oesophageal reflux diseaseAdult: 20 mg daily for 4-8 wk. Maintenance: 10 or 20 mg/day. All doses to be taken once in the morning.Zollinger-Ellison syndromeAdult: Initially, 60 mg once in the morning, adjusted to max dose of 120 mg/day if needed. Daily doses >100 mg should be given in 2 divided doses.Peptic ulcerAdult: 20 mg once in the morning for 4-8 wk (duodenal ulcer) or for 6-12 wk (gastric ulcer).H.pylori infectionAdult: 1-wk triple therapy: 20 mg bid combined w/ clarithromycin 500 mg bid and amoxicillin 1 g bid or combined w/ clarithromycin 250 mg bid and metronidazole 400 mg bid.Erosive oesophagitisAdult: 20 mg/day for 4-8 wk. May continue for another 8 wk if healing is incomplete. Maintenance: 10 or 20 mg/day. All doses to be taken once in the morning.Elderly: No dosage adjustment needed.Hepatic impairment: No dosage adjustment needed. |
| Contraindication | Rabeprazole is contraindicated in patients with known hypersensitivity to Rabeprazole, other PPIs or to any component of the formulation. |
| Mode of Action | Rabeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase at the secretory surface of the gastric parietal cell. |
| Precaution | Gastric malignancy should be ruled out. Severe hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor Mg levels prior to initiation and periodically during prolonged use.LactationRisk SummaryLactation studies have not been conducted to assess presence in human milk, effects on breastfed infant, or effects on milk production; drug is present in rat milk; development and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on breastfed infant from drug or from underlying maternal condition |
| Brand | Beximco Pharmaceuticals Ltd. |
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